Welcome to the REDUCe2 trial webpage
Palliative Long-term Abdominal Drains Versus Repeated Drainage in Untreatable Ascites Due to Advanced Cirrhosis: A Randomised Controlled Trial (REDUCe 2 Study).
Our aims
This study will compare insertion of a palliative tunnelled long-term abdominal drain (LTAD) to standard of care large volume paracentesis (LVP) in the management of refractory ascites.
Patients will be randomised into one of the 2 groups, then followed-up with fortnightly home visits for 3 months. They will have routine bloods taken and will be asked to complete various questionnaires at the visits. Informal caregivers will also be asked to complete a questionnaire monthly.
The study aims to recruit 310 across 35 sites in England, Scotland and Wales. In addition, 30 patients, 20 informal caregivers and 20 Healthcare Professionals will be invited for an optional qualitative interview by SHORE-C (University of Sussex) to give their perceptions and perspectives of LTAD and LVP.